5,2′-Dibromo-2,4′,5′-trihydroxydiphenylmethanone Inhibits LPS-Induced Vascular Inflammation by Targeting the Cav1 Protein

5,2′-Dibromo-2,4′,5′-trihydroxydiphenylmethanone Inhibits LPS-Induced Vascular Inflammation by Targeting the Cav1 Protein

Vascular inflammation is directly responsible for atherosclerosis. 5,2′-Dibromo-2,4′,5′-trihydroxydiphenylmethanone (TDD), a synthetic bromophenol derivative, exhibits anti-atherosclerosis and anti-inflammatory effects. However, the underlying pathways are not yet clear. In this study, we first exam...

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Bibliographic Details
Main Authors: Hongxia Yuan, Qianyi Hou, Xiue Feng, Yuanlin Zhang, Fan Yang, Rui Ge, Qingshan Li
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
5,2′-dibromo-2,4′,5′-trihydroxydiphenylmethanone
lipopolysaccharide
vascular inflammation
caveolin-1
EA.hy926 cells
NF-κB signaling
Online Access:https://www.mdpi.com/1420-3049/27/9/2884

Internet

https://www.mdpi.com/1420-3049/27/9/2884

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