Epalrestat improves motor symptoms by reducing oxidative stress and inflammation in the reserpine induced mouse model of Parkinson’s disease

Epalrestat improves motor symptoms by reducing oxidative stress and inflammation in the reserpine induced mouse model of Parkinson’s disease

Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting a large number of elderly people worldwide. The current therapies for PD are symptom‐based; they do not provide a cure but improve the quality of life. Muscular dysfunction is the hallmark clinica...

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Bibliographic Details
Main Authors: Md. Mahbubur Rahman, Rupali Rani Chakraborti, Md. Abdullah Potol, Ariful Haque Abir, Ozayra Sharmin, Mahabub Alam, Md. Fazlur Rahman Khan, Rownock Afrin, Humayra Jannat, Rasiqh Wadud, Zaki Farhad Habib
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Animal Models and Experimental Medicine
Subjects:
bradykinesia
Epalrestat
glutathione
oxidative‐stress
Parkinson's disease
Online Access:https://doi.org/10.1002/ame2.12097

Internet

https://doi.org/10.1002/ame2.12097

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