Scutellarin Attenuates the IL-1β-Induced Inflammation in Mouse Chondrocytes and Prevents Osteoarthritic Progression

Scutellarin Attenuates the IL-1β-Induced Inflammation in Mouse Chondrocytes and Prevents Osteoarthritic Progression

Osteoarthritis (OA) is a chronic degenerative disease wherein the articular cartilage exhibits inflammation and degradation. Scutellarin (SCU) is a flavonoid glycoside with a range of pharmacological activities, as shown in previous studies demonstrating its anti-inflammatory activity. How SCU impac...

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Bibliographic Details
Main Authors: Zucheng Luo, Zhichao Hu, Yujie Bian, Wenting Su, Xiaoyang Li, Shi Li, Jianbin Wu, Li Shi, Yonghuan Song, Gang Zheng, Wenfei Ni, Jixin Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
scutellarin
chondrocytes
osteoarthritis
inflammation
Nrf2/NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00107/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00107/full

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