Identification of novel immunoregulatory molecules in human thymic regulatory CD4+CD25+ T cells by phage display.

Thymic CD4+CD25+ cells play an important role in immune regulation and are continuously developed in the thymus as an independent lineage. How these cells are generated, what are their multiple pathways of suppressive activity and which are their specific markers are questions that remain unanswered...

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Bibliographic Details
Main Authors: Georgia Porto, Ricardo J Giordano, Luciana C Marti, Beatriz Stolf, Renata Pasqualini, Wadih Arap, Jorge Kalil, Verônica Coelho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3148221?pdf=render