Tolerance induction by exosomes from immature dendritic cells and rapamycin in a mouse cardiac allograft model.

Tolerance induction by exosomes from immature dendritic cells and rapamycin in a mouse cardiac allograft model.

BACKGROUND: Dendritic cells (DCs) release bioactive exosomes that play an important role in immune regulation. Because they express low levels of class I major histocompatibility complex (MHC) and co-stimulatory molecules, exosomes derived from donor immature DCs (imDex) prolong allograft survival b...

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Bibliographic Details
Main Authors: Xiao Li, Jun-Jie Li, Jing-Yue Yang, De-Sheng Wang, Wei Zhao, Wen-Jie Song, Wei-Min Li, Jian-Feng Wang, Wei Han, Zhuo-Chao Zhang, Yong Yu, Da-Yong Cao, Ke-Feng Dou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3430614?pdf=render

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http://europepmc.org/articles/PMC3430614?pdf=render

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