The link between inhibition of PI3K signaling, induction of autophagy, and elimination of organelles to form the lens organelle-free zone
The elimination of organelles to create the lens organelle-free zone (OFZ) is a macroautophagy/autophagy-dependent mechanism that occurs without causing cell death. This process is essential to the ability of the lens to focus incoming images on the retina, as the presence of these organelles would...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | Autophagy Reports |
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| Online Access: | http://dx.doi.org/10.1080/27694127.2022.2080315 |