Pneumonic tularemia in rabbits resembles the human disease as illustrated by radiographic and hematological changes after infection.

Pneumonic tularemia is caused by inhalation of the gram negative bacterium, Francisella tularensis. Because of concerns that tularemia could be used as a bioterrorism agent, vaccines and therapeutics are urgently needed. Animal models of pneumonic tularemia with a pathophysiology similar to the huma...

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Bibliographic Details
Main Authors: Douglas S Reed, Le'kneitah Smith, Tammy Dunsmore, Anita Trichel, Luis A Ortiz, Kelly Stefano Cole, Eileen Barry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3172242?pdf=render