Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy

Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy

Aquaporin-8 (AQP8), a member of the aquaporin family, is strongly expressed in follicular granulosa cells, which could affect the hormone secretion level in females. AQP8, as a membrane protein, could mediate H2O2 into cells, thereby triggering various biological events. The deficiency of Aqp8 incre...

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Bibliographic Details
Main Authors: Binbin Huang, Lingling Jin, Luodan Zhang, Xiaolin Cui, Zhen Zhang, Yongqi Lu, Lujia Yu, Tonghui Ma, He Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
AQP8
hydrogen peroxide
granulosa cell
autophagy
follicular atresia
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.897666/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.897666/full

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