Neutral sphingomyelinase inhibition promotes local and network degeneration in vitro and in vivo

Abstract Background Cell-to-cell communication is vital for tissues to respond, adapt, and thrive in the prevailing milieu. Several mechanisms mediate intercellular signaling, including tunneling nanotubes, gap junctions, and extracellular vesicles (EV). Depending on local and systemic conditions, E...

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Bibliographic Details
Main Authors: Michael L. Risner, Marcio Ribeiro, Nolan R. McGrady, Bhanu S. Kagitapalli, Xitiz Chamling, Donald J. Zack, David J. Calkins
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-023-01291-1