Ex vivo expansion of circulating CD34+ cells enhances the regenerative effect on rat liver cirrhosis

Ex vivo expansion of autologous cells is indispensable for cell transplantation therapy of patients with liver cirrhosis. The aim of this study was to investigate the efficacy of human ex vivo-expanded CD34+ cells for treatment of cirrhotic rat liver. Recipient rats were intraperitoneally injected w...

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Bibliographic Details
Main Authors: Toru Nakamura, Hironori Koga, Hideki Iwamoto, Victor Tsutsumi, Yasuko Imamura, Masako Naitou, Atsutaka Masuda, Yu Ikezono, Mitsuhiko Abe, Fumitaka Wada, Takahiko Sakaue, Takato Ueno, Masaaki Ii, Cantas Alev, Atsuhiko Kawamoto, Takayuki Asahara, Takuji Torimura
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S232905011630167X