Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

Abstract Background The “nonclassic” apparent mineralocorticoid excess (NC-AME) has been identified in approximately 7% of general population. This phenotype is characterized by low plasma renin activity (PRA), high serum cortisol (F) to cortisone (E) ratio, low cortisone, high Fractional Excretion...

Full description

Bibliographic Details
Main Authors: Alejandra Tapia-Castillo, Dominic Guanzon, Carlos Palma, Andrew Lai, Eric Barros, Fidel Allende, Andrea Vecchiola, Carlos E. Fardella, Carlos Salomón, Cristian A. Carvajal
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Translational Medicine
Subjects:
Nonclassic AME
Mineralocorticoid receptor
MicroRNA
Exosomes
Hypertension
Online Access:http://link.springer.com/article/10.1186/s12967-019-02143-8

Internet

http://link.springer.com/article/10.1186/s12967-019-02143-8

Similar Items