Biologically synthesized black ginger-selenium nanoparticle induces apoptosis and autophagy of AGS gastric cancer cells by suppressing the PI3K/Akt/mTOR signaling pathway

Biologically synthesized black ginger-selenium nanoparticle induces apoptosis and autophagy of AGS gastric cancer cells by suppressing the PI3K/Akt/mTOR signaling pathway

Abstract Background Despite being a promising strategy, current chemotherapy for gastric cancer (GC) is limited due to adverse side effects and poor survival rates. Therefore, new drug-delivery platforms with good biocompatibility are needed. Recent studies have shown that nanoparticle-based drug de...

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Bibliographic Details
Main Authors: Rongbo Wang, Keum-yun Ha, Sanjeevram Dhandapani, Yeon-Ju Kim
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Nanobiotechnology
Subjects:
Selenium nanoparticles
Kaempferia parviflora
Gastric cancer
Autophagy
Apoptosis
PI3K/Akt/mTOR
Online Access:https://doi.org/10.1186/s12951-022-01576-6

Internet

https://doi.org/10.1186/s12951-022-01576-6

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