Heme oxygenase-1-transduced bone marrow mesenchymal stem cells in reducing acute rejection and improving small bowel transplantation outcomes in rats

Heme oxygenase-1-transduced bone marrow mesenchymal stem cells in reducing acute rejection and improving small bowel transplantation outcomes in rats

Abstract Background We determined whether bone marrow mesenchymal stem cells (BMMSCs) transduced with heme oxygenase-1 (HO-1), a cytoprotective and immune-protective factor, could improve outcomes for small bowel transplantation (SBTx) in rats. Methods We performed heterotopic SBTx from Brown Norway...

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Bibliographic Details
Main Authors: Yang Yang, Hong Li Song, Wen Zhang, Ben Juan Wu, Nan Nan Fu, Chong Dong, Zhong Yang Shen
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Stem Cell Research & Therapy
Subjects:
Acute cellular rejection
Bone marrow mesenchymal stem cells
Heme oxygenase-1
Small bowel transplantation
Online Access:http://link.springer.com/article/10.1186/s13287-016-0427-8

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http://link.springer.com/article/10.1186/s13287-016-0427-8

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