Melanoma cells induce dedifferentiation and metabolic changes in adipocytes present in the tumor niche
Abstract Background One of the factors that affect the progression of melanoma is the tumor microenvironment, which consists of cellular elements, extracellular matrix, acidification, and a hypoxic state. Adipocytes are one of the types of cell present in the niche and are localized in the deepest l...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
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Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | https://doi.org/10.1186/s11658-023-00476-3 |