Melanoma cells induce dedifferentiation and metabolic changes in adipocytes present in the tumor niche
Abstract Background One of the factors that affect the progression of melanoma is the tumor microenvironment, which consists of cellular elements, extracellular matrix, acidification, and a hypoxic state. Adipocytes are one of the types of cell present in the niche and are localized in the deepest l...
Main Authors: | Aleksandra Simiczyjew, Justyna Wądzyńska, Katarzyna Pietraszek-Gremplewicz, Magdalena Kot, Marcin Ziętek, Rafał Matkowski, Dorota Nowak |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
|
Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | https://doi.org/10.1186/s11658-023-00476-3 |
Similar Items
-
Stromal Cells Present in the Melanoma Niche Affect Tumor Invasiveness and Its Resistance to Therapy
by: Justyna Mazurkiewicz, et al.
Published: (2021-01-01) -
Melanoma Progression under Obesity: Focus on Adipokines
by: Joanna Olszańska, et al.
Published: (2021-05-01) -
Melanoma stimulates the proteolytic activity of HaCaT keratinocytes
by: Justyna Mazurkiewicz, et al.
Published: (2022-09-01) -
Combination of Selected MET and EGFR Inhibitors Decreases Melanoma Cells’ Invasive Abilities
by: Aleksandra Simiczyjew, et al.
Published: (2019-10-01) -
Mutual impact of adipocytes and colorectal cancer cells growing in co-culture conditions
by: Joanna Olszańska, et al.
Published: (2023-06-01)