hiPSC-Derived Schwann Cells Influence Myogenic Differentiation in Neuromuscular Cocultures

hiPSC-Derived Schwann Cells Influence Myogenic Differentiation in Neuromuscular Cocultures

Motoneurons, skeletal muscle fibers, and Schwann cells form synapses, termed neuromuscular junctions (NMJs). These control voluntary body movement and are affected in numerous neuromuscular diseases. Therefore, a variety of NMJ in vitro models have been explored to enable mechanistic and pharmacolog...

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Bibliographic Details
Main Authors: Sarah Janice Hörner, Nathalie Couturier, Roman Bruch, Philipp Koch, Mathias Hafner, Rüdiger Rudolf
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
AChR
acetylcholine receptors
hiPSC
in vitro
neural crest
neuromuscular junction
Online Access:https://www.mdpi.com/2073-4409/10/12/3292

Internet

https://www.mdpi.com/2073-4409/10/12/3292

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