Nicotinamide suppresses bevacizumab-induced epithelial-mesenchymal transition of ARPE-19 cells by attenuating oxidative stress

Nicotinamide suppresses bevacizumab-induced epithelial-mesenchymal transition of ARPE-19 cells by attenuating oxidative stress

AIM: To investigate the effects of nicotinamide (NAM) on bevacizumab (BEV)-induced epithelial-mesenchymal transition (EMT) of human retinal pigment epithelial cells (ARPE-19) and the underling mechanisms. METHODS: ARPE-19 cells were treated with BEV for 24, 48, and 72h, and the variation degrees of...

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Bibliographic Details
Main Authors: Li Zhou, De-Peng Shi, Wen-Juan Chu, Shan Song, Xiang-Hui Hao, Ling-Ling Yang, Hai-Feng Xu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-04-01
Series:International Journal of Ophthalmology
Subjects:
nicotinamide
epithelial-mesenchymal transition
bevacizumab
oxidative stress
arpe-19 cells
Online Access:http://ies.ijo.cn/en_publish/2021/4/20210401.pdf

Internet

http://ies.ijo.cn/en_publish/2021/4/20210401.pdf

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