Tissue and sex-specific programming of DNA methylation by perinatal lead exposure: implications for environmental epigenetics studies

Tissue and sex-specific programming of DNA methylation by perinatal lead exposure: implications for environmental epigenetics studies

Early developmental environment can influence long-term health through reprogramming of the epigenome. Human environmental epigenetics studies rely on surrogate tissues, such as blood, to assess the effects of environment on disease-relevant but inaccessible target tissues. However, the extent to wh...

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Bibliographic Details
Main Authors: Laurie K. Svoboda, Kari Neier, Kai Wang, Raymond G. Cavalcante, Christine A. Rygiel, Zing Tsai, Tamara R. Jones, Siyu Liu, Jaclyn M. Goodrich, Claudia Lalancette, Justin A. Colacino, Maureen A. Sartor, Dana C. Dolinoy
Format: Article
Language:English
Published: Taylor & Francis Group 2021-10-01
Series:Epigenetics
Subjects:
toxicoepigenetics
dna methylation
developmental origins of health and disease (dohad)
surrogate tissue
sex differences
environmental epigenomics
Online Access:http://dx.doi.org/10.1080/15592294.2020.1841872

Internet

http://dx.doi.org/10.1080/15592294.2020.1841872

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