T-Bet Controls Cellularity of Intestinal Group 3 Innate Lymphoid Cells

T-Bet Controls Cellularity of Intestinal Group 3 Innate Lymphoid Cells

Innate lymphoid cells (ILC) play a significant immunological role at mucosal surfaces such as the intestine. T-bet-expressing group 1 innate lymphoid cells (ILC1) are believed to play a substantial role in inflammatory bowel disease (IBD). However, a role of T-bet-negative ILC3 in driving colitis ha...

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Bibliographic Details
Main Authors: Jan-Hendrik Schroeder, Katrin Meissl, Dominika Hromadová, Jonathan W. Lo, Joana F. Neves, Jane K. Howard, Helena Helmby, Nick Powell, Birgit Strobl, Graham M. Lord
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
T-bet
innate lymphoid cells
ILCs
intestinal inflammation
mucosal homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.623324/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.623324/full

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