Notch3 signaling promotes colorectal tumor growth by enhancing immunosuppressive cells infiltration in the microenvironment

Notch3 signaling promotes colorectal tumor growth by enhancing immunosuppressive cells infiltration in the microenvironment

Abstract Background Macrophage infiltration in the tumor microenvironment participates in the regulation of tumor progression. Previous studies have found that Notch signaling pathway is involved in regulating the progression of colorectal cancer (CRC), however, the specific mechanism is still uncle...

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Bibliographic Details
Main Authors: Kai Huang, Wenwu Luo, Jinmei Fang, Changjun Yu, Guangjie Liu, Xiaodong Yuan, Yun Liu, Wenyong Wu
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Cancer
Subjects:
Notch3
Colorectal tumor
Tumor microenvironment
Macrophage infiltration
Online Access:https://doi.org/10.1186/s12885-023-10526-w

Internet

https://doi.org/10.1186/s12885-023-10526-w

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