Minimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets

Minimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets

Glycoprotein VI (GPVI) is a platelet-specific receptor for collagen and fibrin, regulating important platelet functions such as platelet adhesion and thrombus growth. Although the blockade of GPVI function is widely recognized as a potent anti-thrombotic approach, there are limited studies focused o...

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Bibliographic Details
Main Authors: Chao Han, Pengxuan Ren, Medina Mamtimin, Linus Kruk, Edita Sarukhanyan, Chenyu Li, Hans-Joachim Anders, Thomas Dandekar, Irena Krueger, Margitta Elvers, Silvia Goebel, Kristin Adler, Götz Münch, Thomas Gudermann, Attila Braun, Elmina Mammadova-Bach
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
GPVI
collagen
blood platelets
thrombosis
anti-thrombotic therapies
Online Access:https://www.mdpi.com/2227-9059/11/2/423

Internet

https://www.mdpi.com/2227-9059/11/2/423

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