Evaluation of ATOX1 as a Potential Predictive Biomarker for Tetrathiomolybdate Treatment of Breast Cancer Patients with High Risk of Recurrence

Evaluation of ATOX1 as a Potential Predictive Biomarker for Tetrathiomolybdate Treatment of Breast Cancer Patients with High Risk of Recurrence

Copper plays a key role in cancer metastasis, which is the most common cause of cancer death. Copper depletion treatment with tetrathiomolybdate (TM) improved disease-free survival in breast cancer patients with high risk of recurrence in a phase II clinical trial. Because the copper metallochaperon...

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Bibliographic Details
Main Authors: Stéphanie Blockhuys, Camilla Hildesjö, Hans Olsson, Linda Vahdat, Pernilla Wittung-Stafshede
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
breast cancer
ATOX1
copper depletion
tetrathiomolybdate
event-free survival
biomarker
Online Access:https://www.mdpi.com/2227-9059/9/12/1887

Internet

https://www.mdpi.com/2227-9059/9/12/1887

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