NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells

NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells

Abstract Introduction Cytokines of the common γ chain (γc) family are critical for the development, differentiation, and survival of T lineage cells. Cytokines play key roles in immunodeficiencies, autoimmune diseases, allergies, and cancer. Although γc is considered an assistant receptor to transmi...

Full description

Bibliographic Details
Main Authors: Ju A Shim, So Min Lee, Jin Woo Jeong, Hyori Kim, Woo Jae Son, Jun Hong Park, Parkyong Song, Sin-Hyeog Im, Sangsu Bae, Jung-Hyun Park, Yuna Jo, Changwan Hong
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Communication and Signaling
Subjects:
Common gamma chain
TCR signaling
NFAT1
NFκB
T cell activation
Online Access:https://doi.org/10.1186/s12964-023-01326-7

Internet

https://doi.org/10.1186/s12964-023-01326-7

Similar Items