Receptor-mediated transcytosis for brain delivery of therapeutics: receptor classes and criteria

The delivery of therapeutics into the brain is highly limited by the blood-brain barrier (BBB). Although this is essential to protect the brain from potentially harmful material found in the blood, it poses a great challenge for the treatment of diseases affecting the central nervous system (CNS). S...

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Bibliographic Details
Main Authors: Arsalan S. Haqqani, Kasandra Bélanger, Danica B. Stanimirovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Drug Delivery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fddev.2024.1360302/full