Narciclasine induces autophagy-mediated apoptosis in gastric cancer cells through the Akt/mTOR signaling pathway

Narciclasine induces autophagy-mediated apoptosis in gastric cancer cells through the Akt/mTOR signaling pathway

Abstract Background Gastric cancer is a common gastrointestinal cancer and currently has the third-highest mortality rate. Research shows that the natural compound narciclasine has a variety of biological activities. The present study aimed to investigate the effect of narciclasine on gastric cancer...

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Bibliographic Details
Main Authors: Yunfeng Yuan, Xue He, Xiang Li, Yan Liu, Yueliang Tang, Huiming Deng, Xinyuan Shi
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Pharmacology and Toxicology
Subjects:
Narciclasine
Gastric cancer
Autophagy
Apoptosis
Akt/mTOR pathway
Online Access:https://doi.org/10.1186/s40360-021-00537-3

Internet

https://doi.org/10.1186/s40360-021-00537-3

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