Glomerular capillary C3 deposition as a risk factor for unfavorable renal outcome in pediatric primary focal segmental glomerular sclerosis

Glomerular capillary C3 deposition as a risk factor for unfavorable renal outcome in pediatric primary focal segmental glomerular sclerosis

IntroductionSome patients with primary focal segmental sclerosis (FSGS) demonstrate complement 3 (C3) deposition in glomerular capillary loops (Cap-C3) and/or mesangial area (Mes-C3). The clinicopathological and prognostic significance of C3 deposition remains incompletely investigated, especially i...

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Bibliographic Details
Main Authors: Yingchao Peng, Banghai Li, Xiaojie Li, Tao Ju, Zhiqiang Zhang, Peipei Wang, Tao Sun, Jiaping Shu, Meiqiu Wang, Xiaoyi Sun, Huangyu Chen, Chunlin Gao, Zhengkun Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pediatrics
Subjects:
focal segmental glomerular sclerosis
capillary c3 deposition
renal outcome
risk factor
children
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1137375/full

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https://www.frontiersin.org/articles/10.3389/fped.2023.1137375/full

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