Building in vitro 3D human multicellular models of high-grade serous ovarian cancer

Summary: Three-dimensional (3D), multicellular in vitro models provide a useful platform for studying human cancer biology, particularly through deconvolution of the tumor microenvironment, or where animal models do not recapitulate the human condition. Here, we detail a protocol for building human...

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Bibliographic Details
Main Authors: Beatrice Malacrida, Oliver M.T. Pearce, Frances R. Balkwill
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721007929