Evolutionarily conserved gene expression patterns for affective disorders revealed using cross-species brain transcriptomic analyses in humans, rats and zebrafish

Abstract Widespread, debilitating and often treatment-resistant, depression and other stress-related neuropsychiatric disorders represent an urgent unmet biomedical and societal problem. Although animal models of these disorders are commonly used to study stress pathogenesis, they are often difficul...

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Bibliographic Details
Main Authors: Konstantin A. Demin, Nataliya A. Krotova, Nikita P. Ilyin, David S. Galstyan, Tatyana O. Kolesnikova, Tatyana Strekalova, Murilo S. de Abreu, Elena V. Petersen, Konstantin N. Zabegalov, Allan V. Kalueff
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22688-x