Movement disorders are linked to TDP-43 burden in the substantia nigra of FTLD-TDP brain donors

Movement disorders are linked to TDP-43 burden in the substantia nigra of FTLD-TDP brain donors

Abstract Movement disorders (MD) have been linked to degeneration of the substantia nigra (SN) in Parkinson’s disease and include bradykinesia, rigidity, and tremor. They are also present in frontotemporal dementia (FTD), where MD have been linked to frontotemporal lobar degeneration with tau pathol...

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Bibliographic Details
Main Authors: Luigi Fiondella, Priya Gami-Patel, Christian A. Blok, Annemieke J. M. Rozemuller, Jeroen J. M. Hoozemans, The Netherlands Brain Bank, Yolande A. L. Pijnenburg, Marta Scarioni, Anke A. Dijkstra
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Acta Neuropathologica Communications
Subjects:
Frontotemporal Dementia
Frontotemporal Lobar Degeneration
TDP-43
Substantia nigra
Movement disorders
Brain donors
Online Access:https://doi.org/10.1186/s40478-023-01560-7

Internet

https://doi.org/10.1186/s40478-023-01560-7

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