A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea

A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea

The mammalian auditory sensory epithelium has one of the most stereotyped cellular patterns known in vertebrates. Mechano-sensory hair cells are arranged in precise rows, with one row of inner and three rows of outer hair cells spanning the length of the spiral-shaped sensory epithelium. Aiding such...

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Bibliographic Details
Main Authors: Meenakshi Prajapati-DiNubila, Ana Benito-Gonzalez, Erin Jennifer Golden, Shuran Zhang, Angelika Doetzlhofer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-06-01
Series:eLife
Subjects:
inner ear
cochlea
activin signaling
follistatin
hair cell
auditory cell differentiation
Online Access:https://elifesciences.org/articles/47613

Internet

https://elifesciences.org/articles/47613

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