Is hematoxylin-eosin staining in rectal mucosal and submucosal biopsies still useful for the diagnosis of Hirschsprung disease?

Is hematoxylin-eosin staining in rectal mucosal and submucosal biopsies still useful for the diagnosis of Hirschsprung disease?

Abstract Background Hematoxylin-eosin (HE) staining of a full-thickness rectal wall fragment is classically used for the diagnosis of Hirschsprung disease (HD). However, this technique requires large fragments for a better diagnosis. Additionally, the histochemical and immunohistochemical methods of...

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Bibliographic Details
Main Authors: Suellen Serafini, Maria Mercês Santos, Ana Cristina Aoun Tannuri, Maria Claudia Nogueira Zerbini, Maria Cecília de Mendonça Coelho, Josiane de Oliveira Gonçalves, Uenis Tannuri
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Diagnostic Pathology
Subjects:
Hirschsprung’s disease
Rectal biopsy
Acetylcholinesterase, Hematoxylin-eosin
Calretinin
Online Access:http://link.springer.com/article/10.1186/s13000-017-0673-9

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http://link.springer.com/article/10.1186/s13000-017-0673-9

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