The Traumatic Inoculation Process Affects TSPO Radioligand Uptake in Experimental Orthotopic Glioblastoma

The Traumatic Inoculation Process Affects TSPO Radioligand Uptake in Experimental Orthotopic Glioblastoma

Background: The translocator protein (TSPO) has been proven to have great potential as a target for the positron emission tomography (PET) imaging of glioblastoma. However, there is an ongoing debate about the potential various sources of the TSPO PET signal. This work investigates the impact of the...

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Bibliographic Details
Main Authors: Lukas Gold, Enio Barci, Matthias Brendel, Michael Orth, Jiying Cheng, Sabrina V. Kirchleitner, Laura M. Bartos, Dennis Pötter, Maximilian A. Kirchner, Lena M. Unterrainer, Lena Kaiser, Sibylle Ziegler, Lorraine Weidner, Markus J. Riemenschneider, Marcus Unterrainer, Claus Belka, Joerg-Christian Tonn, Peter Bartenstein, Maximilian Niyazi, Louisa von Baumgarten, Roland E. Kälin, Rainer Glass, Kirsten Lauber, Nathalie L. Albert, Adrien Holzgreve
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomedicines
Subjects:
TSPO PET and autoradiography
glioblastoma
traumatic brain injury (TBI)
orthotopic implantation
immunohistochemistry
Online Access:https://www.mdpi.com/2227-9059/12/1/188

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https://www.mdpi.com/2227-9059/12/1/188

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