Iron Neurotoxicity and Protection by Deferoxamine in Intracerebral Hemorrhage

Iron Neurotoxicity and Protection by Deferoxamine in Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) is a subtype of stroke that is characterized by high morbidity and mortality, for which clinical outcome remains poor. An extensive literature indicates that the release of ferrous iron from ruptured erythrocytes in the hematoma is a key pathogenic factor in ICH-induce...

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Bibliographic Details
Main Authors: Zhe Li, Yang Liu, Ruixue Wei, Suliman Khan, Ruiyi Zhang, Yan Zhang, Voon Wee Yong, Mengzhou Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
intracerebral hemorrhage
brain edema
deferoxamine
iron overload
neuronal death
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.927334/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.927334/full

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