P14<sup>ARF</sup>: The Absence that Makes the Difference
P14<sup>ARF</sup> is a tumor suppressor encoded by the CDKN2a locus that is frequently inactivated in human tumors. P14<sup>ARF</sup> protein quenches oncogene stimuli by inhibiting cell cycle progression and inducing apoptosis. P14<sup>ARF</sup> functions can be...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/11/7/824 |