Trypanosoma cruzi and Its Soluble Antigens Induce NET Release by Stimulating Toll-Like Receptors.

Neutrophils release fibrous traps of DNA, histones, and granule proteins known as neutrophil extracellular traps (NETs), which contribute to microbicidal killing and have been implicated in autoimmunity. The role of NET formation in the host response to nonbacterial pathogens is not well-understood....

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Bibliographic Details
Main Authors: Daniel Sousa-Rocha, Mariana Thomaz-Tobias, Larissa Figueiredo Alves Diniz, Priscila Silva Sampaio Souza, Phileno Pinge-Filho, Karina Alves Toledo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4591979?pdf=render