Extracellular Nicotinamide Phosphoribosyltransferase Is a Therapeutic Target in Experimental Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency of prematurity. Postulated mechanisms leading to inflammatory necrosis of the ileum and colon include activation of the pathogen recognition receptor Toll-like receptor 4 (TLR4) and decreased levels of transforming growth...

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Bibliographic Details
Main Authors: Melissa D. Halpern, Akash Gupta, Nahla Zaghloul, Senthilkumar Thulasingam, Christine M. Calton, Sara M. Camp, Joe G. N. Garcia, Mohamed Ahmed
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/12/5/970