Initiating Events in Direct Cardiomyocyte Reprogramming

Summary: Direct reprogramming of fibroblasts into cardiomyocyte-like cells (iCM) holds great potential for heart regeneration and disease modeling and may lead to future therapeutic applications. Currently, application of this technology is limited by our lack of understanding of the molecular mecha...

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Bibliographic Details
Main Authors: Kimberly Sauls, Todd M. Greco, Li Wang, Meng Zou, Michelle Villasmil, Li Qian, Ileana M. Cristea, Frank L. Conlon
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718300792