Machine learning predictor PSPire screens for phase-separating proteins lacking intrinsically disordered regions
Abstract The burgeoning comprehension of protein phase separation (PS) has ushered in a wealth of bioinformatics tools for the prediction of phase-separating proteins (PSPs). These tools often skew towards PSPs with a high content of intrinsically disordered regions (IDRs), thus frequently undervalu...
Main Authors: | , , , , , |
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פורמט: | Article |
שפה: | English |
יצא לאור: |
Nature Portfolio
2024-03-01
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סדרה: | Nature Communications |
גישה מקוונת: | https://doi.org/10.1038/s41467-024-46445-y |