Compression and evaluation of extended release matrix pellets prepared by the extrusion/spheronization process into disintegrating tablets
In this study, a novel approach for compression of matrix pellets into disintegrating tablets has been studied in an attempt to overcome the issues pertaining to rupture of polymer coat during compression of reservoir-type pellets. Extended release matrix pellets were prepared by the extrusion/spher...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Universidade de São Paulo
2012-03-01
|
Series: | Brazilian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100014 |