Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism

Energy production is the most fundamentally important cellular activity supporting all other functions, particularly in highly active organs, such as brains. Here, we summarise transcriptome analyses of young adult (pre-disease) brains from a collection of 11 early-onset familial Alzheimer's di...

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Bibliographic Details
Main Authors: Karissa Barthelson, Morgan Newman, Michael Lardelli
Format: Article
Language:English
Published: The Company of Biologists 2022-01-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/15/1/dmm049187