Enhancing the antibacterial activity of antimicrobial peptide PMAP-37(F34-R) by cholesterol modification

Enhancing the antibacterial activity of antimicrobial peptide PMAP-37(F34-R) by cholesterol modification

Abstract Background The problem of increasing resistance against conventional antibiotics has drawn people’s attention. Therefore, the development of novel antibacterial agents with effective and safe therapeutic effects is imminent. Antimicrobial peptides (AMPs) are considered a promising class of...

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Bibliographic Details
Main Authors: Liangliang Chen, Tengfei Shen, Yongqing Liu, Jiangfei Zhou, Shuaibing Shi, Yang Wang, Zhanqin Zhao, Zhiling Yan, Chengshui Liao, Chen Wang
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Veterinary Research
Subjects:
Antimicrobial peptide PMAP-37(F34-R)
Cholesterol
Hydrophobicity
Antibacterial activity
Therapeutic efficacy
Online Access:http://link.springer.com/article/10.1186/s12917-020-02630-x

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http://link.springer.com/article/10.1186/s12917-020-02630-x

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