Cell-Type-Specific Complement Expression in the Healthy and Diseased Retina

Cell-Type-Specific Complement Expression in the Healthy and Diseased Retina

Summary: Complement dysregulation is a feature of many retinal diseases, yet mechanistic understanding at the cellular level is limited. Given this knowledge gap about which retinal cells express complement, we performed single-cell RNA sequencing on ∼92,000 mouse retinal cells and validated our res...

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Bibliographic Details
Main Authors: Diana Pauly, Divyansh Agarwal, Nicholas Dana, Nicole Schäfer, Josef Biber, Kirsten A. Wunderlich, Yassin Jabri, Tobias Straub, Nancy R. Zhang, Avneesh K. Gautam, Bernhard H.F. Weber, Stefanie M. Hauck, Mijin Kim, Christine A. Curcio, Dwight Stambolian, Mingyao Li, Antje Grosche
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314068

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http://www.sciencedirect.com/science/article/pii/S2211124719314068

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