Specific IgG glycosylation differences precede relapse in PR3-ANCA associated vasculitis patients with and without ANCA rise

Specific IgG glycosylation differences precede relapse in PR3-ANCA associated vasculitis patients with and without ANCA rise

IntroductionImmunoglobulin G (IgG) contains a conserved N-glycan in the fragment crystallizable (Fc), modulating its structure and effector functions. In anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) alterations of IgG Fc-glycosylation have been observed to correlate with t...

Full description

Bibliographic Details
Main Authors: Iwona Wojcik, Manfred Wuhrer, Peter Heeringa, Coen A. Stegeman, Abraham Rutgers, David Falck
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
immunoglobulin G
fucosylation
glycopeptides
glycosylation
anti-neutrophil cytoplasmic antibody–associated vasculitis
mass spectrometry
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1214945/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1214945/full

Similar Items