Phage Lambda P Protein: Trans-Activation, Inhibition Phenotypes and their Suppression

Phage Lambda P Protein: Trans-Activation, Inhibition Phenotypes and their Suppression

The initiation of bacteriophage λ replication depends upon interactions between the oriλ DNA site, phage proteins O and P, and E. coli host replication proteins. P exhibits a high affinity for DnaB, the major replicative helicase for unwinding double stranded DNA. The concept of P-lethality relates...

Full description

Bibliographic Details
Main Authors: Connie Hayes, Wen Wang, Kristen Marciniuk, Sidney Hayes, Monique A. Horbay, Craig Erker
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Viruses
Subjects:
E. coli DnaB replicative helicase
bacteriophage lambda (λ) replication initiation protein P
allelic alterations of dnaB and P
ColE1 plasmid curing and replication inhibition
cellular filamentation
Online Access:http://www.mdpi.com/1999-4915/5/2/619

Internet

http://www.mdpi.com/1999-4915/5/2/619

Similar Items