High-resolution modeling of transmembrane helical protein structures from distant homologues.

Eukaryotic transmembrane helical (TMH) proteins perform a wide diversity of critical cellular functions, but remain structurally largely uncharacterized and their high-resolution structure prediction is currently hindered by the lack of close structural homologues. To address this problem, we presen...

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Bibliographic Details
Main Authors: Kuang-Yui M Chen, Jiaming Sun, Jason S Salvo, David Baker, Patrick Barth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4031050?pdf=render