Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue
Difficulty achieving complete, specific, and homogenous staining is a major bottleneck preventing the widespread use of tissue clearing techniques to image large volumes of human tissue. In this manuscript, we describe a procedure to rapidly design immunostaining protocols for antibody labeling of c...
Main Authors: | Theodore J Zwang, Rachel E Bennett, Maria Lysandrou, Benjamin Woost, Anqi Zhang, Charles M Lieber, Douglas S Richardson, Bradley T Hyman |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2023-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/84112 |
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