Experimental - Theoretical approach for determination of Metformin solubility in supercritical carbon dioxide: Thermodynamic modeling
Metformin, as an anti-hyperglycemic, is the main medicine for treating diabetes of type II. However, its daily dose is high due to its incomplete absorption and short half-life, which leads to digestive problems and patient complaints. Controlled release and increased bioavailability of this drug ca...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | Case Studies in Thermal Engineering |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214157X22008863 |