Experimental - Theoretical approach for determination of Metformin solubility in supercritical carbon dioxide: Thermodynamic modeling

Metformin, as an anti-hyperglycemic, is the main medicine for treating diabetes of type II. However, its daily dose is high due to its incomplete absorption and short half-life, which leads to digestive problems and patient complaints. Controlled release and increased bioavailability of this drug ca...

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Bibliographic Details
Main Authors: Kumar Venkatesan, Saad M. Alshahrani, Amal M. Alsubaiyel, Maram H. Abduljabbar, Manal E. Alosaimi, Maria Grishina, Saeed Shirazian
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Case Studies in Thermal Engineering
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214157X22008863