Synthesis, Complexation Properties, and Evaluation of New Aminodiphosphonic Acids as Vector Molecules for <sup>68</sup>Ga Radiopharmaceuticals

Synthesis, Complexation Properties, and Evaluation of New Aminodiphosphonic Acids as Vector Molecules for <sup>68</sup>Ga Radiopharmaceuticals

Two new aminodiphosphonic acids derived from salicylic acid and its phosphonic analogue were prepared through a simple and efficient synthesis. 2-[(2-Amino-2,2-diphosphono)ethyloxy]-benzoic acid <b>8</b> and 2-[(2-amino-2,2-diphosphono)ethyloxy]-5-ethyl-phenylphosphonic acid <b>9&l...

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Bibliographic Details
Main Authors: Alesya Ya. Maruk, Valery V. Ragulin, Iurii A. Mitrofanov, Galina S. Tsebrikova, Vitaly P. Solov’ev, Alexandr S. Lunev, Kristina A. Lunyova, Olga E. Klementyeva, Vladimir E. Baulin, Galina E. Kodina, Aslan Yu. Tsivadse
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
<sup>68</sup>Ga
diphosphonate
aminodiphosphonic acid
stability constant
radiopharmaceutical
bone-seeking
Online Access:https://www.mdpi.com/1420-3049/26/8/2357

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https://www.mdpi.com/1420-3049/26/8/2357

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