Detection of the ADGRG6 hotspot mutations in urine for bladder cancer early screening by ARMS‐qPCR

Detection of the ADGRG6 hotspot mutations in urine for bladder cancer early screening by ARMS‐qPCR

Abstract Background In bladder cancer, recurrent ADGRG6 enhancer hotspot mutations (chr. 6: 142,706,206 G>A, chr. 6:142,706,209 C>T) were reported at a high mutation rate of approximately 50%. Thus, ADGRG6 enhancer mutation status might be a candidate for diagnostic biomarker. Methods To impro...

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Bibliographic Details
Main Authors: Dan Tan, Wenqi Jiang, Rixin Hu, Zhuoran Li, Tong Ou
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Cancer Medicine
Subjects:
ADGRG6
ARMS‐qPCR
bladder cancer
genetic mutation
liquid biopsy
Online Access:https://doi.org/10.1002/cam4.5879

Internet

https://doi.org/10.1002/cam4.5879

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