Effects of dual blockade in heart failure and renal dysfunction: Systematic review and meta-analysis

Objective: The effect of dual renin–angiotensin system (RAS) inhibition in heart failure (HF) is still controversial. Systematic reviews have shown that dual RAS blockade may reduce mortality and hospitalizations, yet it has been associated with the increased risk of renal dysfunction (RD). Surprisi...

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Bibliographic Details
Main Authors: Alessandra Rodrigues Silva, Alexandre Goes Martini, Graziela De Luca Canto, Eliete Neves da Silva Guerra, Francisco de Assis Rocha Neves
Format: Article
Language:English
Published: SAGE Publications 2019-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320319882656